Completed Grants from the National Blood Sector Research and Development Program

Round

Chief Investigator

Funding Recipient

Research Type

Title and Publications

1

Dr Jane Ford

The University of Sydney

PBM

Effects of antenatal haemoglobin and obstetric transfusion on adverse maternal outcomes

• Outcomes associated with transfusion in low-risk women with obstetric haemorrhage
• The association between haemoglobin levels in the first 20 weeks of pregnancy and pregnancy outcomes
• Haemoglobin trajectories during pregnancy and associated outcomes using pooled maternity and hospitalization data from two tertiary hospitals
• Validation of anaemia, haemorrhage and blood disorder reporting in hospital data in New South Wales, Australia
• Reporting of gestational diabetes and other maternal medical conditions

1

Prof Russell Dale

The University of Sydney

Ig

Improving the use of intravenous immunoglobulin (IVIg) in children with neurological disorders

• Intravenous immunoglobulin in paediatric neurology: safety, adherence to guidelines, and long-term outcome
• Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination

1

Dr Geoff Simon

University of Sunshine Coast

PBM

Clinical characteristics of geriatric patients transfused within 24 hours of Emergency Department presentation

• Outcomes of restrictive versus liberal transfusion strategies in older adults from nine randomised controlled trials: a systematic review and meta-analysis
• Impact and implications of the ageing population on anaemia management, patient blood management and unplanned blood use - University of the Sunshine Coast, Queensland (dissertation)

1

Dr Julie Lee

The University of Queensland

PBM

A series of studies on a new clotting test in pregnant women to optimise the management of bleeding

• The influence of obesity on coagulation in healthy term pregnancy as assessed by rotational thromboelastometry
• Baseline parameters for rotational thromboelastometry in healthy labouring women: a prospective observational study
• Baseline parameters for rotational thromboelastometry (ROTEM®) in healthy pregnant Australian women: a comparison of labouring and non-labouring women at term
• Baseline parameters for rotational thromboelastometry (ROTEM®) in healthy women undergoing elective caesarean delivery: a prospective observational study in Australia

1

Dr James Winearls

The University of Queensland

PBM

Fibrinogen Replacement in Severe Traumatic Haemorrhage

• Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial
• Haemotherapy algorithm for the management of trauma-induced coagulopathy: an Australian perspective

1

Associate Prof Deborah Long

Griffith University

PBM

Improving blood sampling practice for critically ill children undergoing cardiac surgery 

• Patient blood management in critically ill children undergoing cardiac surgery: A cohort study
• Patient blood management in critically ill children undergoing cardiac surgery: A cohort study

1

Prof Bernd Froessler

The University of Adelaide

PBM

Iron need in pregnancy and after birth

• Testing equivalence of two doses of intravenous iron to treat iron deficiency in pregnancy: A randomised controlled trial - Froessler

1

Dr David Burgner

Murdoch Children’s Research Institute

Ig

Towards a better understanding of doctors’ treatment patterns and immunoglobulin use in Australian children with Kawasaki Disease: an opportunity for improvement?

• Epidemiology of Kawasaki disease in Australia using two nationally complete datasets
• Prospective characterisation of SARS-CoV-2 infections among children presenting to tertiary paediatric hospitals across Australia in 2020: a national cohort study
• Coronavirus and Kawasaki disease in children: it's an intriguing but unproven link

1

Prof Erica Wood

Monash University

Ig

Oral antibiotics or intravenous immunoglobulin to reduce infections in patients with blood cancers

• Managing hypogammaglobulinaemia secondary to haematological malignancies in Australia and New Zealand: a clinician survey
• Rational: A randomised controlled feasibility trial comparing prophylactic immunoglobulin with antibiotics in patients with acquired hypogammaglobulinemia secondary to haematological malignancies
• Interventions to reduce infections in patients with hematological malignancies: a systematic review and meta-analysis

2

Associate Prof Elizabeth Ellen Gardiner

Australian National University

Ig

Improved strategies in management of immune thrombocytopenia

• Novel scientific approaches and future research directions in understanding ITP

2

Associate Prof Seng Chai Chua

Western Sydney Health District

PBM

The effect of intravenous iron and blood transfusion on patient outcomes in women with low haemoglobin after birth

2

Dr Bronwyn Pearse

University of the Sunshine Coast

PBM

Implementing Evidence Based Bleeding Management in Cardiac Surgery

• Bleeding Management Practices of Australian Cardiac Surgeons, Anesthesiologists and Perfusionists: A Cross-Sectional National Survey Incorporating the Theoretical Domains Framework (TDF) and COM-B Model
• Barriers and facilitators to implementing evidence based bleeding management in Australian Cardiac Surgery Units: a qualitative interview study analysed with the theoretical domains framework and COM-B model

2

Prof Erica Wood

Monash University

Ig

Improving national immunoglobulin stewardship and clinical outcomes for patients with myeloma (IMPROVE)

2

Dr Michelle Roets

The University of Queensland

PBM

Intraoperative cell salvage a safer and cost effective alternative to allogeneic blood transfusion

• Intraoperative Cell Salvage as an Alternative to Allogeneic (Donated) Blood Transfusion: A Prospective Observational Evaluation of the Immune Response Profile

2

Dr Alison Mo

Monash University

PBM

Understanding risks and clinical outcomes of anaemia in the elderly to inform transfusion policy

• Red cell transfusions: Is less always best?

3

Dr Philip Crispin

Australian National University

PBM

Transfusion Strategies for Low Platelets

• Cryoprecipitate as an alternative to platelet transfusion in thrombocytopenia

3

Prof John Fraser

University of Queensland

PBM

Novel fluid alternatives to blood transfusion to treat acute and chronic blood loss

• An Ovine Model of Hemorrhagic Shock and Resuscitation, to Assess Recovery of Tissue Oxygen Delivery and Oxygen Debt, and Inform Patient Blood Management

4

Prof Anthony Harris

Monash University

PBM

Evaluate the impact of the perioperative patient blood management guidelines on blood use, patient outcomes and costs for cardiac surgery

• Impact of patient blood management guidelines on blood transfusions and patient outcomes during cardiac surgery
• Economic Evaluation of National Patient Blood Management Clinical Guidelines in Cardiac Surgery

4

Dr Nicholas Crump

The University of Melbourne

Ig

Neuromuscular ultrasound as a Biomarker in CIDP

• A Retrospective Study of Ultrasound Accuracy for the Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy

4

Associate Prof David Roxby

Flinders University

PBM

Evaluation of transfusion triggers in elderly patients admitted to the intensive care unit (ICU) and the prevalence of anaemia on discharge from ICU and hospital

• Anaemia in elderly patients at discharge from intensive care and hospital

4

Dr Brenton Sanderson

Macquarie University

PBM

Computerised support for decision-making during massive transfusion to improve efficiency and outcomes

• How well does your massive transfusion protocol perform? A scoping review of quality indicators
• Massive transfusion experience, current practice and decision support: A survey of Australian and New Zealand anaesthetists
• Reply to comment on: Massive transfusion experience, current practice and decision support: A survey of Australian and New Zealand Anaesthetists - Brenton J Sanderson, Jeremy D Field, Lise J Estcourt, Erica M Wood, Enrico W Coiera, 2022